Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryan

Contributors

This material was contributed to by:

Anup Kumar avatar Anup Kumarorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoMo Heydarian avatar Mo Heydarianorcid logoHelena Rasche avatar Helena RascheMélanie Petera avatar Mélanie Peteraorcid logoPavankumar Videm avatar Pavankumar VidemVivek Bhardwaj avatar Vivek BhardwajFidel Ramirez avatar Fidel RamirezTorsten Houwaart avatar Torsten HouwaartFriederike Dündar avatar Friederike Dündarorcid logoLucille Delisle avatar Lucille Delisleorcid logoMallory Freeberg avatar Mallory Freebergorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoBérénice Batut avatar Bérénice Batutorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoFlorian Heyl avatar Florian HeylLeily Rabbani avatar Leily Rabbaniorcid logoMaria Doyle avatar Maria Doyleorcid logoBjörn Grüning avatar Björn Grüningorcid logoYvan Le Bras avatar Yvan Le BrasDevon Ryan avatar Devon RyanMehmet Tekman avatar Mehmet TekmanNiall Beard avatar Niall BeardJoachim Wolff avatar Joachim Wolfforcid logoSaskia Hiltemann avatar Saskia HiltemannEkaterina Polkh avatar Ekaterina Polkh

Funding

These individuals or organisations provided funding support for the development of this resource

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UFR
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de.NBI
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ELIXIR Europe
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CRC992